Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures.

Journal: Journal of translational medicine
PMID: 40082895

Abstract

BACKGROUND: Prior studies have elucidated that alterations in gut microbiota are associated with a spectrum of tumors and metabolic disorders. However, the diagnostic value of gut microbiota in epithelial ovarian cancer remains insufficiently investigated.

Authors

  • Cheng Chen
    Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, China.
  • Chengyuan Deng
    Hunan Traditional Chinese Medical College, Zhuzhou, China.
  • Yanwen Li
    AI Research Lab, Imsight Technology Co., Ltd., Shenzhen, Guangdong, China.
  • Shuguang He
    Department of Clinical Laboratory, The First Affiliated Hospital of Hunan Traditional Chinese Medical College, Hunan Province Directly Affiliated TCM Hospital, Zhuzhou, China.
  • Yunhong Liu
    Department of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China.
  • Shuwen Pan
    Department of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China.
  • Wenqian Xu
    Changsha Center for Disease Prevention and Control, Changsha, China.
  • Lu Fang
  • Yixi Zhu
    Department of Clinical Laboratory, The First Affiliated Hospital of Hunan Traditional Chinese Medical College, Hunan Province Directly Affiliated TCM Hospital, Zhuzhou, China.
  • Yingying Wang
    Department of Thyroid Surgery, China-Japan Union Hospital of Jilin University, Jilin University, Changchun, China.
  • Xiaoxin Jiang
    Department of Clinical Laboratory, People's Hospital of Longhua, Shenzhen, China. jiangxiaoxin168@126.com.

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