AIMC Topic: Carcinoma, Ovarian Epithelial
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Identifying ovarian cancer with machine learning DNA methylation pattern analysis.
Scientific reports
Jul 1, 2025
The majority of patients with epithelial ovarian cancer (EOC) continue to be diagnosed at an advanced stage despite great advances in this disease treatment. To impact overall survival, we need better methods of EOC early diagnosis. We performed a ca...
Integrative analysis of epigenetic and transcriptional interrelations identifies histotype-specific biomarkers in early-stage ovarian carcinoma.
Journal of ovarian research
May 19, 2025
BACKGROUND: Epithelial ovarian cancer (EOC) is a deadly and heterogenous disease comprising five major histotypes: clear cell carcinoma (CCC), endometrioid carcinoma (EC), low- and high-grade serous carcinoma (LGSC, HGSC), and mucinous carcinoma (MC)...
Prediction of Clavien Dindo Classification ≥ Grade III Complications After Epithelial Ovarian Cancer Surgery Using Machine Learning Methods.
Medicina (Kaunas, Lithuania)
Apr 10, 2025
Ovarian cancer surgery requires multiple radical resections with a high risk of complications. The aim of this single-centre, retrospective study was to determine the best method for predicting Clavien-Dindo grade ≥ III complications using machine l...
Deep learning-based analysis of gross features for ovarian epithelial tumors classification: A tool to assist pathologists for frozen section sampling.
Human pathology
Mar 22, 2025
Computational pathology has primarily focused on analyzing tissue slides, neglecting the valuable information contained in gross images. To bridge this gap, we proposed a novel approach leveraging the Swin Transformer architecture to develop a Swin-T...
Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures.
Journal of translational medicine
Mar 13, 2025
BACKGROUND: Prior studies have elucidated that alterations in gut microbiota are associated with a spectrum of tumors and metabolic disorders. However, the diagnostic value of gut microbiota in epithelial ovarian cancer remains insufficiently investi...
Incidence and Predictors of Acute Kidney Injury Following Advanced Ovarian Cancer Cytoreduction at a Tertiary UK Centre: An Exploratory Analysis and Insights from Explainable Artificial Intelligence.
Current oncology (Toronto, Ont.)
Jan 28, 2025
BACKGROUND/OBJECTIVES: The incidence of acute kidney injury (AKI) following advanced epithelial ovarian cancer (EOC) surgery has not been extensively studied. This study aimed to investigate the incidence of AKI and identify preoperative and intraope...
Deep Learning Radiomics Nomogram Based on MRI for Differentiating between Borderline Ovarian Tumors and Stage I Ovarian Cancer: A Multicenter Study.
Academic radiology
Jan 14, 2025
RATIONALE AND OBJECTIVES: To develop and validate a deep learning radiomics nomogram (DLRN) based on T2-weighted MRI to distinguish between borderline ovarian tumors (BOTs) and stage I epithelial ovarian cancer (EOC) preoperatively.
Combination of plasma-based lipidomics and machine learning provides a useful diagnostic tool for ovarian cancer.
Journal of pharmaceutical and biomedical analysis
Nov 2, 2024
Ovarian cancer (OC), the second leading cause of death among gynecological cancers, is often diagnosed at an advanced stage due to its asymptomatic nature at early stages. This study aimed to explore the diagnostic potential of plasma-based lipidomic...
Comparing survival of older ovarian cancer patients treated with neoadjuvant chemotherapy versus primary cytoreductive surgery: Reducing bias through machine learning.
Gynecologic oncology
Mar 29, 2024
OBJECTIVE: To develop and evaluate a multidimensional comorbidity index (MCI) that identifies ovarian cancer patients at risk of early mortality more accurately than the Charlson Comorbidity Index (CCI) for use in health services research.
Identifying Explainable Machine Learning Models and a Novel SFRP2 Fibroblast Signature as Predictors for Precision Medicine in Ovarian Cancer.
International journal of molecular sciences
Nov 29, 2023
Ovarian cancer (OC) is a type of malignant tumor with a consistently high mortality rate. The diagnosis of early-stage OC and identification of functional subsets in the tumor microenvironment are essential to the development of patient management st...
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