Prediction of significant congenital heart disease in infants and children using continuous wavelet transform and deep convolutional neural network with 12-lead electrocardiogram.

Journal: BMC pediatrics
PMID:

Abstract

BACKGROUND: Congenital heart disease (CHD) affects approximately 1% of newborns and is a leading cause of mortality in early childhood. Despite the importance of early detection, current screening methods, such as pulse oximetry and auscultation, have notable limitations, particularly in identifying non-cyanotic CHD. (AI)-assisted electrocardiography (ECG) analysis offers a cost-effective alternative to conventional CHD detection. However, most existing models have been trained on older children, limiting their generalizability to infants and young children. This study developed an AI model trained on real-world ECG data for the detection of hemodynamically significant CHD in children under five years of age.

Authors

  • Yu-Shin Lee
    Division of Cardiology, Department of Pediatrics, Chang Gung Memoral Hospital Linkou Branch, Taoyuan, Taiwan.
  • Hung-Tao Chung
    Division of Cardiology, Department of Pediatrics, Chang Gung Memoral Hospital Linkou Branch, Taoyuan, Taiwan.
  • Jainn-Jim Lin
    Division of Pediatric Intensive Care, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou Branch, Taoyuan, Taiwan.
  • Mao-Sheng Hwang
    Division of Cardiology, Department of Pediatrics, Chang Gung Memoral Hospital Linkou Branch, Taoyuan, Taiwan.
  • Hao-Chuan Liu
    Department of Spine Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun, Jilin, China.
  • Hsin-Mao Hsu
    Division of Cardiology, Department of Pediatrics, Chang Gung Memoral Hospital Linkou Branch, Taoyuan, Taiwan.
  • Ya-Ting Chang
    Division of Cardiology, Department of Pediatrics, Chang Gung Memoral Hospital Linkou Branch, Taoyuan, Taiwan.
  • Syu-Jyun Peng
    Biomedical Electronics Translational Research Center, National Chiao Tung University, Hsin-Chu, Taiwan; Institute of Electronics, National Chiao Tung University, Hsin-Chu, Taiwan. Electronic address: blue.year@msa.hinet.net.