Unraveling relevant cross-waves pattern drifts in patient-hospital risk factors among hospitalized COVID-19 patients using explainable machine learning methods.

Journal: BMC infectious diseases
PMID: 40234758

Abstract

BACKGROUND: Several studies explored factors related to adverse clinical outcomes among COVID-19 patients but lacked analysis of the impact of the temporal data shifts on the strength of association between different predictors and adverse outcomes. This study aims to evaluate factors related to patients and hospitals in the prediction of in-hospital mortality, need for invasive mechanical ventilation (IMV), and intensive care unit (ICU) transfer throughout the pandemic waves.

Authors

  • Fernanda Cristina Barbosa Lana
    Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, Belo Horizonte, 6627, Brazil. fernandacblana@gmail.com.
  • Carolina Coimbra Marinho
    Department of Internal Medicine, Medical School & Telehealth Center, University Hospital, Universidade Federal de Minas Gerais, Av. Professor Alfredo Balena, Belo Horizonte, 110, Brazil.
  • Bruno Barbosa Miranda de Paiva
    Computer Science Department, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, Belo Horizonte, 6627, Brazil.
  • Lucas Rocha Valle
    Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, Belo Horizonte, 6627, Brazil.
  • Guilherme Fonseca do Nascimento
    Universidade Federal de São João del-Rei. Praça Dom Helvécio, São João del-Rei, 74, Brazil.
  • Leonardo Chaves Dutra da Rocha
    Universidade Federal de São João del-Rei. Praça Dom Helvécio, São João del-Rei, 74, Brazil.
  • Marcelo Carneiro
    Hospital Santa Cruz. R. Fernando Abott, Santa Cruz do Sul, 174, Brazil.
  • Joanna d'Arc Lyra Batista
    Hospital Regional do Oeste. R. Florianópolis, Chapecó, 1448 E, Brazil.
  • Fernando Anschau
    Hospital Nossa Senhora da Conceição, Av. Francisco Trein, Porto Alegre, 326, Brazil.
  • Pedro Gibson Paraiso
    Instituto Orizonti. Praça Engenheiro Flávio Gutierrez, Belo Horizonte, Brazil.
  • Frederico Bartolazzi
    Hospital Santo Antônio, Praça Dr. Márcio Carvalho Lopes Filho, Curvelo, 501, Brazil.
  • Christiane Corrêa Rodrigues Cimini
    Hospital Santa Rosália, R. Dr. Onofre, 575, Centro, Teófilo Otoni, Brazil.
  • Alexandre Vargas Schwarzbold
    Department of Internal Medicine, Universidade Federal de Santa Maria, Santa Maria, Brazil.
  • Danyelle Romana Alves Rios
    Universidade Federal de São, João del-Rei/ Campus Centro Oeste Dona Lindu, Divinópolis, Brazil.
  • Marcos André Gonçalves
    Computer Science Department, Universidade Federal de Minas Gerais, Av. Presidente Antônio Carlos, Belo Horizonte, 6627, Brazil.
  • Milena Soriano Marcolino
    Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.

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