Machine Learning-Guided Fluid Resuscitation for Acute Pancreatitis Improves Outcomes.

Journal: Clinical and translational gastroenterology
PMID:

Abstract

INTRODUCTION: Ariel Dynamic Acute Pancreatitis Tracker (ADAPT) is an artificial intelligence tool using mathematical algorithms to predict severity and manage fluid resuscitation needs based on the physiologic parameters of individual patients. Our aim was to assess whether adherence to ADAPT fluid recommendations vs standard management impacted clinical outcomes in a large prospective cohort.

Authors

  • Niwen Kong
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Patrick Chang
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Ira A Shulman
    Department of Pathology, University of Southern California, Los Angeles, California, USA.
  • Ubayd Haq
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Maziar Amini
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Denis Nguyen
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Farhaad Khan
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Rachan Narala
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Nisha Sharma
    Leeds Teaching Hospital NHS Trust, Department of Radiology, Leeds, UK.
  • Daniel Wang
    Department of Ophthalmology and Visual Sciences - Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois.
  • Tiana Thompson
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Jonathan Sadik
    Division of Gastroenterology, Department of Medicine, University of Southern California, Los Angeles, California, USA.
  • Cameron Breze
    Ariel Precision Medicine, Pittsburgh, Pennsylvania, USA.
  • David C Whitcomb
    Ariel Precision Medicine, Pittsburgh, Pennsylvania, USA.
  • James L Buxbaum
    Division of Gastrointestinal and Liver Diseases, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA.