Signal transduction and targeted therapy
Jan 14, 2026
Acute pancreatitis is a complex inflammatory condition characterized by sudden onset and rapid progression, with severe cases often associated with high mortality. In recent years, the global incidence of acute pancreatitis has been increasing, with ...
OBJECTIVES: Growing evidence suggests that vaccines targeting respiratory pathogens have non-specific and broader effects. We aimed to investigate the non-specific effects of respiratory vaccines on acute lower respiratory infection (ALRI) hospitalis...
Hematological biomarkers have emerged as powerful tools in diagnosing Acute Heart Failure (AHF). This study introduces a novel diagnostic framework that integrates Explainable Artificial Intelligence (XAI) with Morris Sensitivity Analysis (MSA) to en...
This retrospective cross-sectional study aimed to elucidate the clinical and imaging characteristics of chronic temporomandibular disorder (TMD) compared to acute TMD in adolescents, and to identify factors associated with symptom chronicity. The stu...
BACKGROUND: Offline reinforcement learning (RL) has been increasingly applied to clinical decision-making problems. However, due to the lack of a standardized pipeline, prior work often relied on strategies that may lead to overfitted policies and in...
This study aims to forecast the spread of acute diarrhoea and dengue diseases in India by conducting a comparative analysis of statistical, mathematical (compartmental), and deep learning time series models. Utilizing weekly reported cases and fatali...
INTRODUCTION: Artificial intelligence (AI) is increasingly being recognized as a transformative force in healthcare, showing significant promise in supporting healthcare professionals. AI has many applications in healthcare, including providing real-...
BACKGROUND: Classification of risk levels in patients with acute pancreatitis remains a difficult task. Although some biomarkers have emerged to predict the prognosis of patients with acute pancreatitis, they have not been widely used in clinical pra...
BACKGROUND: Acute viral respiratory infections (AVRIs) rank among the most common causes of hospitalisation worldwide, imposing significant healthcare burdens and driving the development of pharmacological treatments. However, inconsistent outcome re...
Acute lactational mastitis is a frequently occurring complication for lactating women, exerting a certain degree of influence on their physical condition, breastfeeding, mental health, and daily life. The etiology of this disease is complex, and the ...
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