Robust Diagnosis of Acute Bacterial and Viral Infections via Host Gene Expression Rank-Based Ensemble Machine Learning Algorithm: A Multi-Cohort Model Development and Validation Study.

Abstract

Authors

• Yifei Shen
  Department of Computing, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
• Dongsheng Han
  Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Wenxin Qu
  Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Fei Yu
  Department of Nutrition and food hygiene, College of Public Health of Zhengzhou University, Zhengzhou, China, 450001. Electronic address: 53615631@qq.com.
• Dan Zhang
  School of Pharmacy, Southwest Medical University, Luzhou 646000, China.
• Yifan Xu
  Department of Nutrition and Food Hygiene, School of Public Health, Peking University, 38 Xue Yuan Road, Haidian District, Beijing 100191, China. xuyifan_1992@163.com.
• Enhui Shen
  Institute of Crop Science & Institute of Bioinformatics, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China.
• Qinjie Chu
  Institute of Bioinformatics, Zhejiang University, Hangzhou, China.
• Michael P Timko
  Departments of Biology and Public Health Sciences, University of Virginia, Charlottesville, VA, United States.
• Longjiang Fan
  Hainan Institute, Zhejiang University, Sanya 572025, China; Institute of Crop Science & Institute of Bioinformatics, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China.
• Shufa Zheng
  Department of Laboratory Medicine, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
• Yu Chen
  State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

Keywords

External Resources