AIMC Topic: Virus Diseases

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A Review of In Silico Approaches for Discovering Natural Viral Protein Inhibitors in Aquaculture Disease Control.

Journal of fish diseases
Viral diseases pose a significant threat to the sustainability of global aquaculture, causing economic losses and compromising food security. Traditional control methods often demonstrate limited effectiveness, highlighting the need for alternative a...

Plasma cell-free RNA signatures of inflammatory syndromes in children.

Proceedings of the National Academy of Sciences of the United States of America
Inflammatory syndromes, including those caused by infection, are a major cause of hospital admissions among children and are often misdiagnosed because of a lack of advanced molecular diagnostic tools. In this study, we explored the utility of circul...

Combination therapy synergism prediction for virus treatment using machine learning models.

PloS one
Combining different drugs synergistically is an essential aspect of developing effective treatments. Although there is a plethora of research on computational prediction for new combination therapies, there is limited to no research on combination th...

Coordinating virus research: The Virus Infectious Disease Ontology.

PloS one
The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated data is thereby of fundamental concern. Ontologies-structured, controlled, vocabularies-are designed...

Leveraging machine learning to distinguish between bacterial and viral induced pharyngitis using hematological markers: a retrospective cohort study.

Scientific reports
Accurate differentiation between bacterial and viral-induced pharyngitis is recognized as essential for personalized treatment and judicious antibiotic use. From a cohort of 693 patients with pharyngitis, data from 197 individuals clearly diagnosed w...

Could chatbots help devise the next pandemic virus?

Science (New York, N.Y.)
An MIT class exercise suggests AI tools can be used to order a bioweapon, but some are skeptical.

Optimization: Molecular Communication Networks for Viral Disease Analysis Using Deep Leaning Autoencoder.

Computational and mathematical methods in medicine
Developing new treatments for emerging infectious diseases in infectious and noninfectious diseases has attracted a particular attention. The emergence of viral diseases is expected to accelerate; these data indicate the need for a proactive approach...

Divide-and-conquer: machine-learning integrates mammalian and viral traits with network features to predict virus-mammal associations.

Nature communications
Our knowledge of viral host ranges remains limited. Completing this picture by identifying unknown hosts of known viruses is an important research aim that can help identify and mitigate zoonotic and animal-disease risks, such as spill-over from anim...

Machine learning techniques applied to the drug design and discovery of new antivirals: a brief look over the past decade.

Expert opinion on drug discovery
: Drug design and discovery of new antivirals will always be extremely important in medicinal chemistry, taking into account known and new viral diseases that are yet to come. Although machine learning (ML) have shown to improve predictions on the bi...

Using the antibody-antigen binding interface to train image-based deep neural networks for antibody-epitope classification.

PLoS computational biology
High-throughput B-cell sequencing has opened up new avenues for investigating complex mechanisms underlying our adaptive immune response. These technological advances drive data generation and the need to mine and analyze the information contained in...