Advances in pancreatic cancer diagnosis: from DNA methylation to AI-assisted imaging.

Journal: Expert review of molecular diagnostics
Published Date: Jul 1, 2025

Abstract

INTRODUCTION: Pancreatic Cancer (PC) is a highly aggressive tumor that is mainly diagnosed at later stages. Various imaging technologies, such as CT, MRI, and EUS, possess limitations in early PC diagnosis. Therefore, this review article explores the various innovative biomarkers for PC detection, such as DNA methylation, Noncoding RNAs, and proteomic biomarkers, and the role of AI in PC detection at early stages.

Authors

  • Rohit Sharma
    Department of Rasashastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India. Electronic address: rohitsharma@bhu.ac.in.
  • Kumari Komal
    Department of Pharmaceutics, ISF College Pharmacy, Moga, India.
  • Sourabh Kumar
    Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Straße 11, 12489, Berlin, Germany.
  • Rashmi Ghosh
    Department of Pharmaceutics, ISF College Pharmacy, Moga, India.
  • Prachi Pandey
    Department of Quality Assurance, ISF College Pharmacy, Moga, India.
  • Ghanshyam Das Gupta
    Department of Pharmaceutics, ISF College of Pharmacy, GT Road, Moga, Punjab 142001, India.
  • Manish Kumar
    Department of Biophysics, University of Delhi South Campus, New Delhi, India. Electronic address: manish@south.du.ac.in.

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