Non-traditional socio-environmental and geospatial determinants of Alzheimer's disease-related dementia mortality.

Journal: The Science of the total environment
Published Date: Jul 1, 2025

Abstract

IMPORTANCE: Recent data point to the impact of non-traditional environmental and social factors on Alzheimer's Disease-Related Dementias (ADRD) mortality. Our study aimed to determine the extent to which antecedent air pollution, social vulnerability, and geospatial features in the environment associate with ADRD mortality.

Authors

  • Skanda Moorthy
    Department of Medicine, Cardiovascular Research Institute, Case Western Reserve University, Cleveland, OH, USA. Electronic address: stm65@case.edu.
  • Jean-Eudes Dazard
    Harrington Heart and Vascular Institute, University Hospitals, 11100 Euclid Ave, Cleveland, OH 44106, USA.
  • Zhuo Chen
    State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China. Electronic address: gychenzhuo@aliyun.com.
  • Ruby Charak
    Department of Psychological Science, The University of Texas Rio Grande Valley, Edinburg, TX, USA.
  • Shruthika Palanivel
    Department of Medicine, Cardiovascular Research Institute, Case Western Reserve University, Cleveland, OH, USA.
  • Salil Deo
    Department of Surgery, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
  • Sadeer G Al-Kindi
    Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist, Houston, TX, USA.
  • Sanjay Rajagopalan
    Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

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