Two birds with one stone: pre-TAVI coronary CT angiography combined with FFR helps screen for coronary stenosis.

Journal: BMC medical imaging
Published Date: May 26, 2025

Abstract

OBJECTIVES: Since coronary artery disease (CAD) is a common comorbidity in patients with aortic valve stenosis, invasive coronary angiography (ICA) can be avoided if significant CAD can be screened with the non-invasive coronary CT angiography (cCTA). This study aims to evaluate the ability of machine learning-based CT coronary fractional flow reserve (CT-FFR) derived from cCTA to aid in the diagnosis of comorbid CAD in patients undergoing transcatheter aortic valve implantation (TAVI).

Authors

  • Ruihui Wang
    Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
  • Dihao Pan
    Department of Cardiovascular Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Xinlei Sun
    Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
  • Genren Yang
    Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
  • Jianjun Yao
    Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
  • Xiaoyong Shen
    Department of Radiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China. 1197047@zju.edu.cn.
  • Wenbo Xiao
    Department of Neurology, School of Medicine, The Fourth Affiliated Hospital of Zhejiang University, Yiwu, China.

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