Personalized prediction of gait freezing using dynamic mode decomposition.

Journal: Scientific reports
Published Date:

Abstract

Freezing of gait (FoG) is a common severe gait disorder in patients with advanced Parkinson's disease. The ability to predict the onset of FoG episodes early on allows for timely intervention, which is essential for improving the life quality of patients. Machine learning and deep learning, the current methods, face real-time diagnosis challenges due to comprehensive data processing requirements. Their "black box" nature makes interpreting features and classification boundaries difficult. In this manuscript, we explored a dynamic mode decomposition (DMD)-based approach together with optimal delay embedding time to reconstruct and predict the time evolution of acceleration signals, and introduced a triple index based on DMD to predict and classify FoG. Our predictive analysis shows 86.5% accuracy in classification, and an early prediction ratio of 81.97% with an average early prediction time of 6.13 s. This DMD-based approach has the potential for real-time patient-specific FoG prediction.

Authors

  • Zhiwen Fu
    Department of Mathematics and SUSTech International Center for Mathematics, Southern University of Science and Technology, Shenzhen, China.
  • Congping Lin
    School of Mathematics and Statistics, Hubei Key Lab of Engineering Modelling and Scientific, Center for Mathematical Sciences, Huazhong University of Science and Technology, Wuhan, China.
  • Yiwei Zhang
    College of Chemical Engineering, Nanjing Forestry University Nanjing 210037 China njfu2304@163.com +86-25-85427396.