Association of the characteristics of brain magnetic resonance imaging with genes related to disease onset in schizophrenia patients.

Journal: SLAS technology
Published Date: Mar 28, 2025

Abstract

BACKGROUND: Schizophrenia (SCH) is a complex neurodevelopmental disorder, whose pathogenesis is not fully elucidated. This article aims to reveal disease-specific brain structural and functional changes and their potential genetic basis by analyzing the characteristics of brain magnetic resonance imaging (MRI) in SCH patients and related gene expression patterns.

Authors

  • Jiantu Lin
    Department of Radiology, Xiamen Xianyue Hospital, Xianyue Hospital Affiliated with Xiamen Medical College, Fujian Psychiatric Center, Fujian Clinical Research Center for Mental Disorders, Xiamen, Fujian 361012, China.
  • Bo Wang
    Department of Clinical Laboratory Medicine Center, Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia, China.
  • Shaoguang Chen
    Department of Psychiatry, Xiamen Xianyue Hospital, Xianyue Hospital Affiliated with Xiamen Medical College, Fujian Psychiatric Center, Fujian Clinical Research Center for Mental Disorders, Xiamen, Fujian 361012, China.
  • Fengling Cao
    Department of Clinical Laboratory, Xiamen Xianyue Hospital, Xianyue Hospital Affiliated with Xiamen Medical College, Fujian Psychiatric Center, Fujian Clinical Research Center for Mental Disorders, Xiamen, Fujian 361012, China.
  • Jingbin Zhang
    Artera, Inc., Los Altos, CA.
  • Zirong Lu
    Department of Radiology, Xiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian 361015, China. Electronic address: doctorran20@163.com.

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