Renal Dysfunction Across the Spectrum of Cardiogenic Shock: Mechanisms, Clinical Implications, and Therapeutic Strategies.

Journal: Current heart failure reports
Published Date: Jun 25, 2025

Abstract

PURPOSE OF REVIEW: This review aims to elucidate the complex interplay between cardiogenic shock (CS) and renal function, detailing the mechanisms of kidney injury, identifying risk factors, and providing a framework for the diagnosis and management of acute kidney injury (AKI) in CS. We evaluate evidence supporting medical interventions, including vasopressors, inotropes, and mechanical circulatory support (MCS), in relation to renal outcomes.

Authors

  • Diana De Oliveira-Gomes
    Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA.
  • Christian Guilliod
    Department of Internal Medicine, University of Miami/Jackson Health System, Miami, FL, USA.
  • Ilan Vavilin
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA.
  • Ankeet Bhatt
    Division of Research, Kaiser Permanente Northern California,, San Francisco, CA, USA.
  • Brendon Neuen
    The George Institute for Global Health, University of New South Wales, Sydney, NSW, Australia.
  • Jamie L W Kennedy
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA.
  • Manreet Kanwar
    Division of Cardiology, University of Chicago, Chicago, IL, USA.
  • Megan Terek
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA.
  • Shashank S Sinha
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA.
  • Van-Khue Ton
    Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, USA.
  • Mitchell Psotka
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA.
  • Vanessa Blumer
    Falls Church, Inova Schar Heart and Vascular Institute, Inova Fairfax Medical Campus, 3300 Gallows Road,, Falls Church, VA, 22042, USA. Vanessa.blumer@inova.org.

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