Next questions on gastrointestinal stromal tumors: unresolved challenges and future directions.

Journal: Current opinion in oncology
Published Date:

Abstract

PURPOSE OF REVIEW: Despite remarkable progress in the management of gastrointestinal stromal tumors (GISTs), critical challenges persist. Key aspects such as risk stratification, the optimal duration of adjuvant therapy, and strategies to enhance the efficacy of first-line treatment remain subjects of ongoing debate. This review explores emerging concepts and innovative approaches aimed at refining patient selection and optimizing therapeutic decision-making to further improve clinical outcomes.

Authors

  • Davide Romandini
    Sarcoma Translational Research Group, Vall d'Hebron Institute of Oncology (VHIO).
  • Pawel Sobczuk
    Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Carlo M Cicala
    Sarcoma Translational Research Group, Vall d'Hebron Institute of Oncology (VHIO).
  • César Serrano
    Sarcoma Translational Research Group, Vall d'Hebron Institute of Oncology (VHIO).