Harnessing Artificial Intelligence for Precision Diagnosis and Treatment of Triple Negative Breast Cancer.

Journal: Clinical breast cancer
Published Date:

Abstract

Triple-Negative Breast Cancer (TNBC) is a highly aggressive subtype of breast cancer (BC) characterized by the absence of estrogen, progesterone, and HER2 receptors, resulting in limited therapeutic options. This article critically examines the role of Artificial Intelligence (AI) in enhancing the diagnosis and treatment of TNBC treatment. We begin by discussing the incidence of TNBC and the fundamentals of precision medicine, emphasizing the need for innovative diagnostic and therapeutic approaches. Current diagnostic methods, including conventional imaging techniques and histopathological assessments, exhibit limitations such as delayed diagnosis and interpretative discrepancies. This article highlights AI-driven advancements in image analysis, biomarker discovery, and the integration of multi-omics data, leading to enhanced precision and efficiency in diagnosis and treatment. In treatment, AI facilitates personalized therapeutic strategies, accelerates drug discovery, and enables real-time monitoring of patient responses. However, challenges persist, including issues related to data quality, model interpretability, and the societal impact of AI implementation. In the conclusion, we discuss the future prospects of integrating AI into clinical practice and emphasize the importance of multidisciplinary collaboration. This review aims to outline key trends and provide recommendations for utilizing AI to improve TNBC management outcomes, while highlighting the need for further research.

Authors

  • Md Sadique Hussain
    Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Prem Nagar, Dehradun, Uttarakhand, 248007, India. sadiquehussain007@gmail.com.
  • Prasanna Srinivasan Ramalingam
    Protein Engineering lab, School of Biosciences and Technology, Vellore Institute of Technology, Vellore, Tamil Nadu, India.
  • Gayathri Chellasamy
    Department of Bionanotechnology, Gachon University, Gyeonggi-do, South Korea.
  • Kyusik Yun
    Department of Bionanotechnology, Gachon University, Gyeonggi-do, South Korea.
  • Ajay Singh Bisht
    School of Pharmaceutical Sciences, Shri Guru Ram Rai University, Dehradun, Uttarakhand, India.
  • Gaurav Gupta
    Department of Neurosurgery, Rutgers New Jersey Medical School, Newark, New Jersey.