Towards Investigating Residual Hearing Loss: Quantification of Fibrosis in a Novel Cochlear OCT Dataset.

Journal: IEEE transactions on bio-medical engineering
Published Date: Jul 1, 2025

Abstract

OBJECTIVE: Cochlear implants (CIs) are bionic prostheses that restores hearing via electrical stimulation of the auditory nerve. Hybrid CIs, which use electroacoustic stimulation (EAS), combine residual low-frequency acoustic hearing with CI electrical stimulation. Intracochlear fibrosis, which forms in response to the presence of the implant, may impede residual hearing function and gradually reduce the efficacy of EAS. It is therefore a translational objective to study the formation of cochlear fibrosis in rodents, with the goal of reducing fibrotic burden and improving outcomes for CI patients.

Authors

  • Julia Dietlmeier
    Insight Centre for Data Analytics, Dublin City University, Glasnevin, Dublin 9, Ireland.
  • Benjamin Greenberg
    Department of Psychiatry and Human Behavior, Butler Hospital/Warren Alpert School of Medicine, Brown University, Providence, RI, USA.
  • Wenxuan He
  • Teresa Wilson
    Oregon Health and Science University, Portland, Oregon, USA.
  • Rubing Xing
  • Jordan Hill
  • Adrienne Fettig
  • Madeline Otto
  • Teyhana Rounsavill
  • Lina A J Reiss
  • Jingang Yi
  • Noel E O'Connor
    Insight Centre for Data Analytics, Dublin City University, Glasnevin, Dublin 9, Ireland.
  • George W S Burwood

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