AIMC Topic: Guinea Pigs
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Should we be guinea pigs for Google's artificial intelligence app?
International journal of dermatology
Nov 7, 2021
Computational determination of hERG-related cardiotoxicity of drug candidates.
BMC bioinformatics
May 29, 2019
BACKGROUND: Drug candidates often cause an unwanted blockage of the potassium ion channel of the human ether-a-go-go-related gene (hERG). The blockage leads to long QT syndrome (LQTS), which is a severe life-threatening cardiac side effect. Therefore...
An evaluation of selected (Q)SARs/expert systems for predicting skin sensitisation potential.
SAR and QSAR in environmental research
Apr 20, 2018
Predictive testing to characterise substances for their skin sensitisation potential has historically been based on animal models such as the Local Lymph Node Assay (LLNA) and the Guinea Pig Maximisation Test (GPMT). In recent years, EU regulations, ...
Synchrony measure for a neuron driven by excitatory and inhibitory inputs and its adaptation to experimentally-recorded data.
Bio Systems
Sep 15, 2017
The aim of the current work is twofold: firstly to adapt an existing method measuring the input synchrony of a neuron driven only by excitatory inputs in such a way so as to account for inhibitory inputs as well and secondly to further appropriately ...
Characterizing the Input-Output Function of the Olfactory-Limbic Pathway in the Guinea Pig.
Computational intelligence and neuroscience
Jul 28, 2015
Nowadays the neuroscientific community is taking more and more advantage of the continuous interaction between engineers and computational neuroscientists in order to develop neuroprostheses aimed at replacing damaged brain areas with artificial devi...
Towards Investigating Residual Hearing Loss: Quantification of Fibrosis in a Novel Cochlear OCT Dataset.
IEEE transactions on bio-medical engineering
Jul 1, 2025
OBJECTIVE: Cochlear implants (CIs) are bionic prostheses that restores hearing via electrical stimulation of the auditory nerve. Hybrid CIs, which use electroacoustic stimulation (EAS), combine residual low-frequency acoustic hearing with CI electric...
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