Alzheimer's disease and driving: review of the literature and consensus guideline from Belgian dementia experts and the Belgian road safety institute endorsed by the Belgian Medical Association.

Journal: Acta neurologica Belgica
PMID:

Abstract

Alzheimer's disease (AD) is a highly prevalent condition and its prevalence is expected to further increase due to the aging of the general population. It is obvious that the diagnosis of AD has implications for driving. Finally, driving discussions are also emotionally charged because driving is associated with independence and personal identity. However, it is not clear how to implement this in clinical practice and the Belgian law on driving is rather vague in its referral to neurodegenerative brain diseases in general nor does it provide clear-cut instructions for dementia or AD compared to for example driving for patients with epilepsy and as such does not prove to be very helpful. The present article reviews what is known from both literature and existing guidelines and proposes a consensus recommendation tailored to the Belgian situation agreed by both AD experts and the Belgian Road Safety Institute endorsed by the Belgian Medical Association. It is concluded that the decision about driving fitness should be considered as a dynamic process where the driving fitness is assessed and discussed early after diagnosis and closely monitored by the treating physician. The diagnosis of AD on itself definitely does not imply the immediate and full revocation of a driving license nor does it implicate a necessary referral for a formal on-road driving assessment. There is no evidence to recommend a reduced exposure or a mandatory co-pilot. A MMSE-based framework to trichotomise AD patients as safe, indeterminate or unsafe is presented. The final decision on driving fitness can only be made after careful history taking and clinical examination, neuropsychological, functional and behavioral evaluation and, only for selected cases, a formal assessment of driving performance.

Authors

  • Jan Versijpt
    Department of Neurology, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090, Brussels, Belgium. jan.versijpt@uzbrussel.be.
  • Mark Tant
    CARA Department, Centre for Fitness to Drive, Belgian Road Safety Institute, Brussels, Belgium.
  • Ingo Beyer
    Geriatric Department, UZ Brussel, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
  • Jean-Christophe Bier
    Department of Neurology, Erasme Hospital, Université Libre de Bruxelles, Brussels, Belgium.
  • Patrick Cras
    Born Bunge Institute and Antwerp University Hospital, University of Antwerp, Wilrijk, Belgium.
  • Peter P De Deyn
    Laboratory of Neurochemistry and Behavior, Reference Center for Biological Markers of Dementia, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Patrick De Wit
    Department of Neurology, AZ Sint Jozef, Malle, Belgium.
  • Olivier Deryck
    Department of Neurology, AZ St Jan, Brugge, Belgium.
  • Bernard Hanseeuw
    Department of Neurology, Saint Luc University Clinic and Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium.
  • Margareta Lambert
    Department of Geriatrics, AZ St Jan, Brugge, Belgium.
  • Jean-Claude Lemper
    Afdeling Geriatrie, SILVA Medical, Scheutbos, Brussels, Belgium.
  • Eric Mormont
    Department of Neurology, Université Catholique de Louvain, CHU UCL Namur, Godinne, Belgium.
  • Mirko Petrovic
    Department of Internal Medicine (Geriatrics), Ghent University, Ghent, Belgium.
  • Gaetane Picard
    Department of Neurology and Memory Clinic, Clinique Saint-Pierre, Ottignies, Belgium.
  • Eric Salmon
    Memory Clinic, Service of Neurology, CHU Liège, Liège, Belgium.
  • Kurt Segers
    Memory Clinic, CHU Brugmann, Brussels, Belgium.
  • Anne Sieben
    Neurology Department, Gent University Hospital, Gent, Belgium.
  • Evert Thiery
    Neurology Department, Gent University Hospital, Gent, Belgium.
  • Jos Tournoy
    Geriatric Medicine and Memory Clinic, University Hospitals Leuven, Leuven, Belgium.
  • Maurits Vandewoude
    Universitair Centrum Geriatrie and ZNA St Elisabeth, Universiteit Antwerpen, Antwerpen, Belgium.
  • Manfredi Ventura
    Direction Médicale and Services des Neurosciences, Grand Hôpital de Charleroi, Charleroi, Belgium.
  • Jurn Verschraegen
    Expertisecentrum Dementie Vlaanderen, Antwerp, Belgium.
  • Sebastiaan Engelborghs
    Laboratory of Neurochemistry and Behavior, Reference Center for Biological Markers of Dementia, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
  • Tom Goffin
    Ordre des Medicins/Orde der Artsen, Brussels, Belgium.
  • Michel Deneyer
    Ordre des Medicins/Orde der Artsen, Brussels, Belgium.
  • Adrian Ivanoiu
    Department of Neurology, Saint Luc University Clinic and Institute of Neuroscience, Université Catholique de Louvain, Brussels, Belgium.