Integrative multi-omics analysis reveals BEST1 as a potential tumor-associated gene in gliomas.

Journal: Neuroscience
Published Date: Aug 6, 2025

Abstract

BACKGROUND: The newest glioma classification in WHO 2021 emphasizes the importance of gene mutations in the glioma molecular pathogenesis. Our research aims to look for new glioma-related genes that have the potential to be therapeutic targets.

Authors

  • Zili Qiu
    Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou 221002, China.
  • Chengcheng Guo
    Department of Endocrinology and Metabolism, Peking University People's Hospital, Beijing, China.
  • Xuejiao Liu
    Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou 221002, China.
  • Shangfeng Gao
    Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou 221002, China.
  • Weihan Xiao
    Department of Ultrasound, The Second Clinical Medical College, North Sichuan Medical College, Nan Chong, China.
  • Hai Cheng
    Ningbo Institute for Food Control, Ningbo 315048, China.
  • Luxin Yin
    Department of Neurosurgery, The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, China; Institute of Nervous System Diseases, Xuzhou Medical University, Xuzhou 221002, China. Electronic address: yinluxin530@163.com.

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