Identification and analysis of pyroptosis-related key genes in heart failure.

Journal: Journal of cardiothoracic surgery
Published Date: Jul 14, 2025

Abstract

BACKGROUND: Pyroptosis plays a pivotal role in the pathogenesis of Heart Failure (HF). However, the current understanding of how pyroptosis-related genes (PRGs) influence HF is scarce. This study aimed to explore the link between PRGs and HF based on bioinformatics.

Authors

  • Jing Zhang
    MOEMIL Laboratory, School of Optoelectronic Information, University of Electronic Science and Technology of China, Chengdu, China.
  • Zhijie Yue
    Department of Cardiovascular Internal Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University,Tongji Shanxi Hospital, Taiyuan, 030032, China.
  • Na Zhu
    Department of Center of Integrated Traditional Chinese and Western Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
  • Na Zhao
    Department of Gynecology, Peking University First Hospital Ningxia Women and Children's Hospital, Yinchuan, Ningxia, China.

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