Development and validation of a keypoint region-based convolutional neural network to automate thoracic Cobb angle measurements using whole-spine standing radiographs.

Journal: Acta neurochirurgica
Published Date: Aug 23, 2025

Abstract

PURPOSE: Adolescent idiopathic scoliosis (AIS) affects a significant portion of the adolescent population, leading to severe spinal deformities if untreated. Diagnosis, surgical planning, and assessment of outcomes are determined primarily by the Cobb angle on anteroposterior spinal radiographs. Screening for scoliosis enables early interventions and improved outcomes. However, screenings are often conducted through school entities where a trained radiologist may not be available to accurately interpret the imaging results.

Authors

  • Mert Marcel Dagli
    Medizinische Universität Innsbruck, Innsbruck, Austria.
  • Jonathan H Sussman
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Jaskeerat Gujral
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Bhargavi R Budihal
    Department of General Medicine, BGS Global Institute of Medical Sciences, Bengaluru, India.
  • Marie Kerr
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Jang W Yoon
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 801 Spruce Street, Philadelphia, PA, 19107, USA. jang.yoon@pennmedicine.upenn.edu.
  • Ali K Ozturk
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 801 Spruce Street, Philadelphia, PA, 19107, USA.
  • Patrick J Cahill
    Division of Orthopaedic Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Jason Anari
    Department of Orthopaedic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Beth A Winkelstein
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • William C Welch
    Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, 801 Spruce Street, Philadelphia, PA, 19107, USA.

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