SE-ATT-YOLO- A deep learning driven ultrasound based respiratory motion compensation system for precision radiotherapy.

Journal: Computers in biology and medicine
Published Date:

Abstract

OBJECTIVE: The therapeutic management of neoplasm employs high level energy beam to ablate malignant cells, which can cause collateral damage to adjacent normal tissue. Furthermore, respiration-induced organ motion, during radiotherapy can lead to significant displacement of neoplasms. In this work, a non-invasive ultrasound-based deep learning algorithm for respiratory motion compensation system (RMCS) was developed to mitigate the effect of respiratory motion induced neoplasm movement in radiotherapy.

Authors

  • Chia-Chun Kuo
    Department of Radiation Oncology, Taipei Medical University Hospital, Taipei, Taiwan; Department of Radiation Oncology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; School of Health Care Administration, College of Management, Taipei Medical University, Taipei, Taiwan.
  • Anoop Gopinathan Pillai
    Department of Mechanical Engineering, National Taipei University of Technology, Taipei, Taiwan.
  • Ai-Ho Liao
    Graduate Institute of Biomedical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan; Department of Biomedical Engineering, National Defense Medical Center, Taipei, Taiwan. Electronic address: aiho@mail.ntust.edu.tw.
  • Hsiao-Wei Yu
    Department of Radiation Oncology, Taipei Medical University Hospital, Taipei, Taiwan; School of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, Taiwan.
  • Subramanian Ramanathan
    Department of Chemical Technology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
  • Hong Zhou
    Department of TCM Orthopedics & Traumatology, Gansu province hospital of TCM, Lanzhou, China.
  • Catherin Meena Boominathan
    PG & Research Department of Chemistry, Bishop Heber College, Tiruchirappalli-620017, India.
  • Shiu-Chen Jeng
    Department of Radiation Oncology, Taipei Medical University Hospital, Taipei, Taiwan; School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
  • Jeng-Fong Chiou
    Department of Hospice and Palliative Care, Taipei Medical University Hospital, Taipei, Taiwan.
  • Ho-Chiao Chuang
    Department of Mechanical Engineering, National Taipei University of Technology, Taipei, Taiwan.