Machine learning on encephalographic activity may predict opioid analgesia.

Journal: European journal of pain (London, England)
Published Date:

Abstract

BACKGROUND: Opioids are used for the treatment of pain. However, 30-50% of patients have insufficient effect to the opioid initially selected by the physician, and there is an urgent need for biomarkers to select responders to the most appropriate drug. Since opioids mediate their effect in the central nervous system, this study aimed to investigate if electroencephalography (EEG) during rest or pain before treatment could predict the analgesic response.

Authors

  • M Gram
    Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Denmark.
  • C Graversen
    Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Denmark.
  • A E Olesen
    Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Denmark.
  • A M Drewes
    Mech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, Denmark.