Artificial Neural Networks approach to pharmacokinetic model selection in DCE-MRI studies.
Journal:
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Published Date:
Nov 19, 2016
Abstract
PURPOSE: In pharmacokinetic analysis of Dynamic Contrast Enhanced MRI data, a descriptive physiological model should be selected properly out of a set of candidate models. Classical techniques suggested for this purpose suffer from issues like computation time and general fitting problems. This article proposes an approach based on Artificial Neural Networks (ANNs) for solving these problems.