[Comparative analysis of two assaysin detection of sperm DNA fragmentation index, flow cytometry and AI-based fluorescence microscopy, based on AO staining: A multicentre study].

Journal: Zhonghua nan ke xue = National journal of andrology
PMID: 38639663

Abstract

OBJECTIVE: To study the correlation, consistency, and variations between two assays of DNA fragmentation index based on acridine orange (AO) staining via AI-based fluorescence microscopy(AI-DFI), and flow cytometry (FCM-DFI) across multiple centers.

Authors

  • Lai-Qing Zhu
    Department of Andrology,Drum Tower Clinical College of Nanjing Medical University，Nanjing, jiangsu 210008, China.
  • Liang Shi
    Department of Andrology,Drum Tower Clinical College of Nanjing Medical University，Nanjing, jiangsu 210008,China.
  • Xiao-Yu Yang
    Reproduction Center,The First Affiliated hospital with Nanjing Medical University, Nanjing, jiangsu 210009, China.
  • Yi-Feng Ge
    Reproduction Center, Eastern Theatre General Hospital, Nanjing, jiangsu 210002, China.
  • Yu-Tian Dai
    Department of Andrology,Drum Tower Clinical College of Nanjing Medical University，Nanjing, jiangsu 210008, China.

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