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Spermatozoa

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Artificial intelligence model for the assessment of unstained live sperm morphology.

Reproduction & fertility
ABSTRACT: Traditional sperm morphology assessment requires staining and high magnification (100×), rendering sperm unsuitable for further use. We aimed to determine whether an in-house artificial intelligence (AI) model could reliably assess normal s...

Semen collection, semen analysis and artificial insemination in the kākāpō (Strigops habroptilus) to support its conservation.

PloS one
The critically endangered kākāpō (Strigops habroptilus) has suffered population declines due to habitat loss, hunting, and predation. Conservation efforts, including translocation to predator-free islands, have helped increase numbers of this flightl...

A potential supplemental indication of dipyridamole for contraception: Dipyridamole inhibits mouse sperm fertilization capacity in vitro.

Biochemical and biophysical research communications
The inhibition of sperm cAMP and ATP levels, using an FDA-approved medication, may impair sperm motility and, consequently, fertilization, thus paving the way for the development of a male contraceptive. The objective of this study was to define the ...

Multimodal distribution and its impact on the accurate assessment of spermatozoa morphological data: Lessons from machine learning.

Animal reproduction science
Objective assessment of sperm morphology is an essential component for assessing ejaculate quality. Due to economic limitations, investigators often divert to conducting observational studies instead of experimental ones, which provide the strongest ...

Development of a deep-learning model for detecting positive tubules during sperm recovery for nonobstructive azoospermia.

Reproduction (Cambridge, England)
To enhance surgical testicular sperm retrieval outcome for men with nonobstructive azoospermia, a deep-learning model was developed to identify positive seminiferous tubules by labeling 110 images with sperm-containing tubules sampled during microdis...

[Application of Artificial Intelligence in Sperm Quality Analysis and Sperm Screening].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
Infertility is a global health issue, and more and more people are hoping to have babies by means of assisted reproductive technology. However, there are still many challenges in fertilization and pregnancy outcomes. Sperm quality is a key factor aff...

Artificial intelligence interpretation of touch print smear cytology of testicular specimen from patients with azoospermia.

Journal of assisted reproduction and genetics
PURPOSE: Identification of mature sperm at microdissection testicular sperm extraction (mTESE) is a crucial step of sperm retrieval to help patients with non-obstructive azoospermia (NOA) proceed to intracytoplasmic sperm injection. Touch print smear...

Artificial intelligence in Andrological flow cytometry: The next step?

Animal reproduction science
Since its introduction in animal andrology, flow cytometry (FC) has dramatically evolved. Nowadays, many compartments and functions of the spermatozoa can be analyzed in thousands of spermatozoa, including, but not limited to DNA, acrosome, membrane ...

Modeling and control of a sperm-inspired robot with helical propulsion.

Bioinspiration & biomimetics
Efficient propulsion has been a central focus of research in the field of biomimetic underwater vehicles. Compared to the prevalent fish-like reciprocating flapping propulsion mode, the sperm-like helical propulsion mode features higher efficiency an...

Multi-omics analyses and machine learning prediction of oviductal responses in the presence of gametes and embryos.

eLife
The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate the adaptive interactions between the oviduct and gamete/embryo, we performed a m...