Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways.

Journal: Artificial intelligence in medicine
Published Date:

Abstract

BACKGROUND: Cancer is a disease that involves abnormal cell growth and can invade or metastasize to other tissues. It is known that several factors are related to its initiation, proliferation, and invasiveness. Recently, it has been reported that long non-coding RNAs (lncRNAs) can participate in specific functional pathways and further regulate the biological function of cancer cells. Studies on lncRNAs are therefore helpful for uncovering the underlying mechanisms of cancer biological processes.

Authors

  • Lei Chen
    Department of Chemistry, Stony Brook University Stony Brook NY USA.
  • Yu-Hang Zhang
    Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  • Guohui Lu
    Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang 330006, People's Republic of China. Electronic address: guohui-lu@163.com.
  • Tao Huang
    The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, China.
  • Yu-Dong Cai
    College of Life Science, Shanghai University, Shanghai, People's Republic of China.