Using deep learning to segment breast and fibroglandular tissue in MRI volumes.

Journal: Medical physics
Published Date:

Abstract

PURPOSE: Automated segmentation of breast and fibroglandular tissue (FGT) is required for various computer-aided applications of breast MRI. Traditional image analysis and computer vision techniques, such atlas, template matching, or, edge and surface detection, have been applied to solve this task. However, applicability of these methods is usually limited by the characteristics of the images used in the study datasets, while breast MRI varies with respect to the different MRI protocols used, in addition to the variability in breast shapes. All this variability, in addition to various MRI artifacts, makes it a challenging task to develop a robust breast and FGT segmentation method using traditional approaches. Therefore, in this study, we investigated the use of a deep-learning approach known as "U-net."

Authors

  • Mehmet Ufuk Dalmış
    Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands.
  • Geert Litjens
    Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Katharina Holland
  • Arnaud Setio
    Radboud University Medical Center, Geert Grooteplein 10, 6525 GA, Nijmegen, The Netherlands.
  • Ritse Mann
    Diagnostic Image Analysis Group, Department of Radiology, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Nico Karssemeijer
  • Albert Gubern-Mérida
    Diagnostic Image Analysis Group, Department of Radiology, Radboud University Medical Center, Nijmegen, The Netherlands.