Expert System for Bone Scan Interpretation Improves Progression Assessment in Bone Metastatic Prostate Cancer.

Journal: Advances in therapy
Published Date: Mar 7, 2017

Abstract

INTRODUCTION: The bone scan index (BSI) was introduced as a quantitative tool for tumor involvement in bone of patients with metastatic prostate cancer (mPCa). The computer-aided diagnosis device for BSI analysis EXINIbone seems to represent technical progress for the quantitative assessment of bone involvement. But it is not yet clear if the automated BSI (aBSI) could contribute to improved evaluation of progression in patients under antiandrogens or chemotherapy in contrast to the visual interpretation and/or conventional biomarkers such as the prostate-specific antigen (PSA).

Authors

  • Fabian Haupt
    Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany. Fabian.Haupt@insel.ch.
  • Georg Berding
    Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
  • Ali Namazian
    Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
  • Florian Wilke
    Department of Medical Physics and Radiation Protection, Hannover Medical School, Hannover, Germany.
  • Alena Böker
    Department of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
  • Axel Merseburger
    Department of Urology, University Lübeck, Lübeck, Germany.
  • Lilli Geworski
    Department of Medical Physics and Radiation Protection, Hannover Medical School, Hannover, Germany.
  • Markus Antonius Kuczyk
    Department of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.
  • Frank Michael Bengel
    Department of Nuclear Medicine, Hannover Medical School, Hannover, Germany.
  • Inga Peters
    Department of Urology and Urologic Oncology, Hannover Medical School, Hannover, Germany.

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