Development and Validation of a Deep Learning System for Diabetic Retinopathy and Related Eye Diseases Using Retinal Images From Multiethnic Populations With Diabetes.

Journal: JAMA
Published Date:

Abstract

IMPORTANCE: A deep learning system (DLS) is a machine learning technology with potential for screening diabetic retinopathy and related eye diseases.

Authors

  • Daniel Shu Wei Ting
    Singapore National Eye Center, Singapore Eye Research Institute Singapore Health Service Singapore Singapore.
  • Carol Yim-Lui Cheung
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Gilbert Lim
    School of Computing, National University of Singapore.
  • Gavin Siew Wei Tan
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Nguyen D Quang
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Alfred Gan
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Haslina Hamzah
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Renata Garcia-Franco
    Instituto Mexicano De Oftalmologia, IAP, Queretaro, Mexico.
  • Ian Yew San Yeo
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Shu Yen Lee
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Edmund Yick Mun Wong
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Charumathi Sabanayagam
    Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.
  • Mani Baskaran
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Farah Ibrahim
    Duke-NUS Medical School, National University of Singapore, Singapore.
  • Ngiap Chuan Tan
    Duke-NUS Medical School, National University of Singapore, Singapore.
  • Eric A Finkelstein
    Lien Center for Palliative Care, Health Services and Systems Research Program, Duke-NUS Graduate Medical School, Singapore.
  • Ecosse L Lamoureux
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Ian Y Wong
    Department of Ophthalmology, The University of Hong Kong, Hong Kong SAR, China.
  • Neil M Bressler
    Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland4Editor, JAMA Ophthalmology.
  • Sobha Sivaprasad
    Moorfields Eye Hospital City Road Campus, London, UK.
  • Rohit Varma
    University of Southern California Gayle and Edward Roski Eye Institute, Los Angeles, California.
  • Jost B Jonas
    Department of Ophthalmology, Ruprecht-Karls University of Heidelberg, Heidelberg, Germany.
  • Ming Guang He
    State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Centre, Sun Yatsen University, Guangzhou, China.
  • Ching-Yu Cheng
    Singapore National Eye Centre, Singapore Eye Research Institute, Singapore, Singapore.
  • Gemmy Chui Ming Cheung
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Tin Aung
    Singapore Eye Research Institute, Singapore National Eye Center, Singapore.
  • Wynne Hsu
    School of Computing, National University of Singapore.
  • Mong Li Lee
    School of Computing, National University of Singapore.
  • Tien Yin Wong
    Singapore National Eye Center, Duke-National University of Singapore Medical School, Singapore 168751, Singapore; National Institutes of Health Research Biomedical Research Centre Biomedical Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.