Addressing diagnostic dilemmas in eosinophilic esophagitis using esophageal epithelial eosinophil-derived neurotoxin.

Journal: Journal of pediatric gastroenterology and nutrition
PMID: 38374551

Abstract

OBJECTIVES: Eosinophil-derived neurotoxin (EDN) is a viable marker of eosinophilic esophagitis (EoE) disease activity. We studied the utility of measuring EDN from esophageal epithelial brushings for diagnosing EoE, focusing on two scenarios: (1) cases of exclusive distal eosinophilia and (2) cases of discrepancy between endoscopy and histology.

Authors

  • Jessina Thomas
    Center for Digestive Health and Nutrition, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Puanani Hopson
    Department of Pediatric Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
  • Chirajyoti Deb
    Pediatric Specialty Diagnostic Gastroenterology Translational Lab, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Jeffrey Bornstein
    Center for Digestive Health and Nutrition, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Devendra Mehta
    Center for Digestive Health and Nutrition, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Khaled Bittar
    Center for Digestive Health and Nutrition, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.
  • Yamen Smadi
    Center for Digestive Health and Nutrition, Orlando Health Arnold Palmer Hospital for Children, Orlando, Florida, USA.

Keywords

External Resources

Popular Topics
Recent Journals