Graph-based semi-supervised learning with genomic data integration using condition-responsive genes applied to phenotype classification.

Journal: Journal of the American Medical Informatics Association : JAMIA
Published Date:

Abstract

OBJECTIVE: Data integration methods that combine data from different molecular levels such as genome, epigenome, transcriptome, etc., have received a great deal of interest in the past few years. It has been demonstrated that the synergistic effects of different biological data types can boost learning capabilities and lead to a better understanding of the underlying interactions among molecular levels.

Authors

  • Abolfazl Doostparast Torshizi
    Department of Industrial Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
  • Linda R Petzold
    Department of Computer Science, University of California, Santa Barbara, CA, USA.