Deep Learning Techniques for Automatic MRI Cardiac Multi-Structures Segmentation and Diagnosis: Is the Problem Solved?

Journal: IEEE transactions on medical imaging
Published Date:

Abstract

Delineation of the left ventricular cavity, myocardium, and right ventricle from cardiac magnetic resonance images (multi-slice 2-D cine MRI) is a common clinical task to establish diagnosis. The automation of the corresponding tasks has thus been the subject of intense research over the past decades. In this paper, we introduce the "Automatic Cardiac Diagnosis Challenge" dataset (ACDC), the largest publicly available and fully annotated dataset for the purpose of cardiac MRI (CMR) assessment. The dataset contains data from 150 multi-equipments CMRI recordings with reference measurements and classification from two medical experts. The overarching objective of this paper is to measure how far state-of-the-art deep learning methods can go at assessing CMRI, i.e., segmenting the myocardium and the two ventricles as well as classifying pathologies. In the wake of the 2017 MICCAI-ACDC challenge, we report results from deep learning methods provided by nine research groups for the segmentation task and four groups for the classification task. Results show that the best methods faithfully reproduce the expert analysis, leading to a mean value of 0.97 correlation score for the automatic extraction of clinical indices and an accuracy of 0.96 for automatic diagnosis. These results clearly open the door to highly accurate and fully automatic analysis of cardiac CMRI. We also identify scenarios for which deep learning methods are still failing. Both the dataset and detailed results are publicly available online, while the platform will remain open for new submissions.

Authors

  • Olivier Bernard
  • Alain Lalande
  • Clement Zotti
  • Frederick Cervenansky
  • Xin Yang
    Department of Oral Maxillofacial-Head Neck Oncology, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai, China.
  • Pheng-Ann Heng
  • Irem Cetin
  • Karim Lekadir
    Information and Communication Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain.
  • Oscar Camara
    Department of Information and Communication Technologies, Universitat Pompeu Fabra, Tànger 122-140, Barcelona 08018, Spain.
  • Miguel Ángel González Ballester
    SIMBioSys, Universitat Pompeu Fabra, Barcelona, Spain; ICREA, Barcelona, Spain.
  • Gerard Sanroma
    SIMBioSys, Universitat Pompeu Fabra, Barcelona, Spain.
  • Sandy Napel
  • Steffen Petersen
  • Georgios Tziritas
  • Elias Grinias
  • Mahendra Khened
  • Varghese Alex Kollerathu
  • Ganapathy Krishnamurthi
  • Marc-Michel Rohe
  • Xavier Pennec
  • Maxime Sermesant
  • Fabian Isensee
  • Paul Jager
  • Klaus H Maier-Hein
    Medical Image Computing (MIC), German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: k.maier-hein@dkfz.de.
  • Peter M Full
  • Ivo Wolf
  • Sandy Engelhardt
  • Christian F Baumgartner
  • Lisa M Koch
    Hertie Institute for AI in Brain Health, University of Tübingen, Tübingen, Germany.
  • Jelmer M Wolterink
    Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • Ivana Išgum
    Department of Biomedical Engineering and Physics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.
  • Yeonggul Jang
  • Yoonmi Hong
  • Jay Patravali
  • Shubham Jain
  • Olivier Humbert
    Department of Nuclear Medicine, Centre Georges-François Leclerc, Dijon, France.
  • Pierre-Marc Jodoin
    Université de Sherbrooke, Sherbrooke, Qc, Canada.