CNN models discriminating between pulmonary micro-nodules and non-nodules from CT images.

Journal: Biomedical engineering online
Published Date:

Abstract

BACKGROUND: Early and automatic detection of pulmonary nodules from CT lung screening is the prerequisite for precise management of lung cancer. However, a large number of false positives appear in order to increase the sensitivity, especially for detecting micro-nodules (diameter < 3 mm), which increases the radiologists' workload and causes unnecessary anxiety for the patients. To decrease the false positive rate, we propose to use CNN models to discriminate between pulmonary micro-nodules and non-nodules from CT image patches.

Authors

  • Patrice Monkam
    Sino-Dutch Biomedical and Information Engineering School, Northeastern University, No. 195 Chuangxin Avenue, Hunnan District, Shenyang, 110169, China.
  • Shouliang Qi
    Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Life Science Building, 500 Zhihui Street, Hun'nan District, Shenyang, 110169, China. qisl@bmie.neu.edu.cn.
  • Mingjie Xu
    Sino-Dutch Biomedical and Information Engineering School, Northeastern University, No. 195 Chuangxin Avenue, Hunnan District, Shenyang, 110169, China.
  • Fangfang Han
    Department of Biomedical, Northeast University, Shenyan, China.
  • Xinzhuo Zhao
    Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Life Science Building, 500 Zhihui Street, Hun'nan District, Shenyang, 110169, China.
  • Wei Qian
    Department of Electrical and Computer Engineering, University of Texas at El Paso, 500 West University Avenue, El Paso, TX 79968, USA; Sino-Dutch Biomedical and Information Engineering School, Northeastern University, No.11, Lane 3, Wenhua Road, Heping District, Shenyang, Liaoning 110819, China. Electronic address: wqian@utep.edu.