Onto2Vec: joint vector-based representation of biological entities and their ontology-based annotations.
Journal:
Bioinformatics (Oxford, England)
Published Date:
Jul 1, 2018
Abstract
MOTIVATION: Biological knowledge is widely represented in the form of ontology-based annotations: ontologies describe the phenomena assumed to exist within a domain, and the annotations associate a (kind of) biological entity with a set of phenomena within the domain. The structure and information contained in ontologies and their annotations make them valuable for developing machine learning, data analysis and knowledge extraction algorithms; notably, semantic similarity is widely used to identify relations between biological entities, and ontology-based annotations are frequently used as features in machine learning applications.