Learning-Based Quality Control for Cardiac MR Images.

Journal: IEEE transactions on medical imaging
Published Date:

Abstract

The effectiveness of a cardiovascular magnetic resonance (CMR) scan depends on the ability of the operator to correctly tune the acquisition parameters to the subject being scanned and on the potential occurrence of imaging artifacts, such as cardiac and respiratory motion. In the clinical practice, a quality control step is performed by visual assessment of the acquired images; however, this procedure is strongly operator-dependent, cumbersome, and sometimes incompatible with the time constraints in clinical settings and large-scale studies. We propose a fast, fully automated, and learning-based quality control pipeline for CMR images, specifically for short-axis image stacks. Our pipeline performs three important quality checks: 1) heart coverage estimation; 2) inter-slice motion detection; 3) image contrast estimation in the cardiac region. The pipeline uses a hybrid decision forest method-integrating both regression and structured classification models-to extract landmarks and probabilistic segmentation maps from both long- and short-axis images as a basis to perform the quality checks. The technique was tested on up to 3000 cases from the UK Biobank and on 100 cases from the UK Digital Heart Project and validated against manual annotations and visual inspections performed by expert interpreters. The results show the capability of the proposed pipeline to correctly detect incomplete or corrupted scans (e.g., on UK Biobank, sensitivity and specificity, respectively, 88% and 99% for heart coverage estimation and 85% and 95% for motion detection), allowing their exclusion from the analyzed dataset or the triggering of a new acquisition.

Authors

  • Giacomo Tarroni
    Biomedical Image Analysis Group, Department of Computing, Imperial College London, London, UK.
  • Ozan Oktay
  • Wenjia Bai
    Department of Computing Imperial College London London UK.
  • Andreas Schuh
  • Hideaki Suzuki
    Division of Brain Sciences, Department of Medicine, Imperial College London, London, UK.
  • Jonathan Passerat-Palmbach
  • Antonio de Marvao
    MRC London Institute of Medical Sciences, Imperial College London, London, United Kingdom.
  • Declan P O'Regan
    MRC London Institute of Medical Sciences, Imperial College London, London, United Kingdom.
  • Stuart Cook
  • Ben Glocker
    Kheiron Medical Technologies, London, UK.
  • Paul M Matthews
    Division of Brain Sciences, Imperial College London, London, UK.
  • Daniel Rueckert
    Biomedical Image Analysis (BioMedIA) Group, Department of Computing, Imperial College London, UK. Electronic address: d.rueckert@imperial.ac.uk.