Cancer Care Treatment Outcome Ontology: A Novel Computable Ontology for Profiling Treatment Outcomes in Patients With Solid Tumors.

Journal: JCO clinical cancer informatics
Published Date: Dec 1, 2018

Abstract

PURPOSE: There is as yet no computer-processable resource to describe treatment end points in cancer, hindering our ability to systematically capture and share outcomes data to inform better patient care. To address these unmet needs, we have built an ontology, the Cancer Care Treatment Outcome Ontology (CCTOO), to organize high-level concepts of treatment end points with structured knowledge representation to facilitate standardized sharing of real-world data.

Authors

  • Frank P Lin
    Frank P. Lin and Richard J. Epstein, St Vincent's Hospital and The Kinghorn Cancer Centre; Frank P. Lin, Tudor Groza, Simon Kocbek, and Richard J. Epstein, Garvan Institute of Medical Research, Sydney, Australia; Frank P. Lin, Waikato Hospital, Hamilton, New Zealand; and Erick Antezana, Norwegian University of Science and Technology, Trondheim, Norway.
  • Tudor Groza
    The Garvan Institute of Medical Research, Sydney, Australia.
  • Simon Kocbek
    Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Sydney, Australia; School of Science, RMIT University, Melbourne, Australia; Department of Computing and Information Systems, University of Melbourne, Melbourne, Australia. Electronic address: skocbek@gmail.com.
  • Erick Antezana
    Frank P. Lin and Richard J. Epstein, St Vincent's Hospital and The Kinghorn Cancer Centre; Frank P. Lin, Tudor Groza, Simon Kocbek, and Richard J. Epstein, Garvan Institute of Medical Research, Sydney, Australia; Frank P. Lin, Waikato Hospital, Hamilton, New Zealand; and Erick Antezana, Norwegian University of Science and Technology, Trondheim, Norway.
  • Richard J Epstein
    Department of Oncology, St Vincent's Hospital, The Kinghorn Cancer Centre, 370 Victoria St, Darlinghurst, Sydney, Australia.

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