Importance of medical data preprocessing in predictive modeling and risk factor discovery for the frailty syndrome.

Journal: BMC medical informatics and decision making
PMID:

Abstract

BACKGROUND: Increasing life expectancy results in more elderly people struggling with age related diseases and functional conditions. This poses huge challenges towards establishing new approaches for maintaining health at a higher age. An important aspect for age related deterioration of the general patient condition is frailty. The frailty syndrome is associated with a high risk for falls, hospitalization, disability, and finally increased mortality. Using predictive data mining enables the discovery of potential risk factors and can be used as clinical decision support system, which provides the medical doctor with information on the probable clinical patient outcome. This enables the professional to react promptly and to avert likely adverse events in advance.

Authors

  • Andreas Philipp Hassler
    Holzinger Group, HCI-KDD, Institute for Medical Informatics/Statistics, Medical University Graz, Graz, 8036, Austria.
  • Ernestina Menasalvas
    Universidad Politécnica de Madrid, Centro de Tecnología Biomédica, Spain.
  • Francisco José García-García
    Division of Geriatric Medicine, Virgen del Valle Geriatric Hospital, Toledo, 45000, Spain.
  • Leocadio Rodríguez-Mañas
    Division of Geriatric Medicine, University Hospital of Getafe, Getafe, 28905, Spain.
  • Andreas Holzinger
    Human-Centered AI Lab, Medical University of Graz, Graz, Austria.