ML-DSP: Machine Learning with Digital Signal Processing for ultrafast, accurate, and scalable genome classification at all taxonomic levels.

Journal: BMC genomics
PMID:

Abstract

BACKGROUND: Although software tools abound for the comparison, analysis, identification, and classification of genomic sequences, taxonomic classification remains challenging due to the magnitude of the datasets and the intrinsic problems associated with classification. The need exists for an approach and software tool that addresses the limitations of existing alignment-based methods, as well as the challenges of recently proposed alignment-free methods.

Authors

  • Gurjit S Randhawa
    Department of Computer Science, University of Western Ontario, London, ON, Canada. grandha8@uwo.ca.
  • Kathleen A Hill
    Department of Biology, University of Western Ontario, London, ON, Canada.
  • Lila Kari
    School of Computer Science, University of Waterloo, Waterloo, ON, Canada.