Statistical Approaches Based on Deep Learning Regression for Verification of Normality of Blood Pressure Estimates.

Journal: Sensors (Basel, Switzerland)
Published Date:

Abstract

Oscillometric blood pressure (BP) monitors currently estimate a single point but do not identify variations in response to physiological characteristics. In this paper, to analyze BP's normality based on oscillometric measurements, we use statistical approaches including kurtosis, skewness, Kolmogorov-Smirnov, and correlation tests. Then, to mitigate uncertainties, we use a deep learning method to determine the confidence limits (CLs) of BP measurements based on their normality. The proposed deep learning regression model decreases the standard deviation of error (SDE) of the mean error and the mean absolute error and reduces the uncertainties of the CLs and SDEs of the proposed technique. We validate the normality of the distribution of the BP estimation which fits the standard normal distribution very well. We use a rank test in the deep learning technique to demonstrate the independence of the artificial systolic BP and diastolic BP estimations. We perform statistical tests to verify the normality of the BP measurements for individual subjects. The proposed methodology provides accurate BP estimations and reduces the uncertainties associated with the CLs and SDEs using the deep learning algorithm.

Authors

  • Soojeong Lee
    School of Electronic Engineering, Hanyang University, 222 Wangsimni-ro, Seongdong, Seoul 133-791, Republic of Korea.
  • Gangseong Lee
    Ingenium College, Kwangwoon University, 20 Kwangwoon-ro, Nowon-gu, Seoul 01897, Korea. gslee0115@gmail.com.
  • Gwanggil Jeon
    Department of Embedded Systems Engineering, College of Information Technology, Incheon National University, 119 Academy-ro, Yeonsu-gu, Incheon, 22012, Korea. gjeon@inu.ac.kr.