Machine learning in resting-state fMRI analysis.

Journal: Magnetic resonance imaging
Published Date:

Abstract

Machine learning techniques have gained prominence for the analysis of resting-state functional Magnetic Resonance Imaging (rs-fMRI) data. Here, we present an overview of various unsupervised and supervised machine learning applications to rs-fMRI. We offer a methodical taxonomy of machine learning methods in resting-state fMRI. We identify three major divisions of unsupervised learning methods with regard to their applications to rs-fMRI, based on whether they discover principal modes of variation across space, time or population. Next, we survey the algorithms and rs-fMRI feature representations that have driven the success of supervised subject-level predictions. The goal is to provide a high-level overview of the burgeoning field of rs-fMRI from the perspective of machine learning applications.

Authors

  • Meenakshi Khosla
    School of Electrical and Computer Engineering, Cornell University, USA.
  • Keith Jamison
    Radiology, Weill Cornell Medical College, USA.
  • Gia H Ngo
    School of Electrical and Computer Engineering, Cornell University, United States of America.
  • Amy Kuceyeski
    Radiology, Weill Cornell Medical College, USA; Brain and Mind Research Institute, Weill Cornell Medical College, USA.
  • Mert R Sabuncu
    Department of Radiology, Weill Cornell Medicine, New York, NY, USA.