CT texture analysis for the prediction of KRAS mutation status in colorectal cancer via a machine learning approach.

Journal: European journal of radiology
Published Date: Jul 2, 2019

Abstract

PURPOSE: This study aimed to investigate whether a machine learning-based computed tomography (CT) texture analysis could predict the mutation status of V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) in colorectal cancer.

Authors

  • Narumi Taguchi
    Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
  • Seitaro Oda
    Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan (T.N., N.Y., N.K., Y.N., H.U., M.K., S.O., T.H.).
  • Yasuhiro Yokota
    Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
  • Sadahiro Yamamura
    Department of Radiology, Kumamoto General Hospital, 10-10 Tori-cho, Yatsushiro, Kumamoto, 866-8660, Japan.
  • Masanori Imuta
    Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
  • Tadatoshi Tsuchigame
    Kumamoto General Health Center, 4-11-1 Higashimachi, Higashi-ku, Kumamoto, 862-0901, Japan.
  • Yasunori Nagayama
    Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan (T.N., N.Y., N.K., Y.N., H.U., M.K., S.O., T.H.).
  • Masafumi Kidoh
    Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan (T.N., N.Y., N.K., Y.N., H.U., M.K., S.O., T.H.).
  • Takeshi Nakaura
    Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan (T.N., N.Y., N.K., Y.N., H.U., M.K., S.O., T.H.). Electronic address: kff00712@nifty.com.
  • Shinya Shiraishi
    Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
  • Yoshinori Funama
    Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, Honjo 1-1-1, Kumamoto 860-8556, Japan (Y.F.).
  • Satoru Shinriki
    Department of Molecular Laboratory Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
  • Yuji Miyamoto
  • Hideo Baba
  • Yasuyuki Yamashita
    Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuoku, Kumamoto, 860-8556, Japan. Electronic address: yama@kumamoto-u.ac.jp.

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