Constructing a Consciousness Meter Based on the Combination of Non-Linear Measurements and Genetic Algorithm-Based Support Vector Machine.

Journal: IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
PMID:

Abstract

OBJECTIVE: Constructing a framework to evaluate consciousness is an important issue in neuroscience research and clinical practice. However, there is still no systematic framework for quantifying altered consciousness along the dimensions of both level and content. This study builds a framework to differentiate the following states: coma, general anesthesia, minimally conscious state (MCS), and normal wakefulness.

Authors

  • Zhenhu Liang
  • Shuai Shao
  • Zhe Lv
  • Duan Li
    CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu, 730000, PR China.
  • Jamie W Sleigh
  • Xiaoli Li
    State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
  • Chongyang Zhang
    Key Laboratory of Bioactive Substances and Resource Utilization of Chinese Herbal Medicine, Ministry of Education, China Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, China; School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou, 510006, China; Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, 519087, China.
  • Jianghong He