A combination of 3-D discrete wavelet transform and 3-D local binary pattern for classification of mild cognitive impairment.

Journal: BMC medical informatics and decision making
Published Date:

Abstract

BACKGROUND: The detection of Alzheimer's Disease (AD) in its formative stages, especially in Mild Cognitive Impairments (MCI), has the potential of helping the clinicians in understanding the condition. The literature review shows that the classification of MCI-converts and MCI-non-converts has not been explored profusely and the maximum classification accuracy reported is rather low. Thus, this paper proposes a Machine Learning approach for classifying patients of MCI into two groups one who converted to AD and the others who are not diagnosed with any signs of AD. The proposed algorithm is also used to distinguish MCI patients from controls (CN). This work uses the Structural Magnetic Resonance Imaging data.

Authors

  • Harsh Bhasin
    School of Computer and Systems Sciences, Jawaharlal Nehru University, New Delhi, India. i_harsh_bhasin@yahoo.com.
  • Ramesh Kumar Agrawal
    School of Computer and Systems Sciences, Jawaharlal Nehru University, New Delhi, India.