Fully automated 3D aortic segmentation of 4D flow MRI for hemodynamic analysis using deep learning.

Journal: Magnetic resonance in medicine
Published Date:

Abstract

PURPOSE: To generate fully automated and fast 4D-flow MRI-based 3D segmentations of the aorta using deep learning for reproducible quantification of aortic flow, peak velocity, and dimensions.

Authors

  • Haben Berhane
    Department of Radiology, Feinberg School of Medicine, Northwestern University, 737 N Michigan Ave, Ste 1600, Chicago, IL 60611.
  • Michael Scott
    Department of Biomedical Engineering, Northwestern University, Chicago, Illinois.
  • Mohammed Elbaz
    Department of Biomedical Engineering, Northwestern University, Chicago, Illinois.
  • Kelly Jarvis
    Department of Radiology, Northwestern University, Chicago, Illinois.
  • Patrick McCarthy
    Divison of Cardiac Surgery, Northwestern University, Chicago, Illinois.
  • James Carr
    Department of Biomedical Engineering, Northwestern University, Chicago, Illinois.
  • Chris Malaisrie
    Department of Radiology, Northwestern University, Chicago, Illinois.
  • Ryan Avery
    Department of Radiology, Northwestern University, Chicago, Illinois.
  • Alex J Barker
    Department of Biomedical Engineering and Physics (J.T.P.) and Department of Radiology & Nuclear Medicine (P.v.O.), Academic Medical Center, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Department of Radiology (B.D.A., J.C.C., M.M.), Department of Medicine-Cardiology (R.O.B., L.C.), and Department of Biomedical Engineering (M.M.), Northwestern University, Chicago, Ill; and Department of Radiology & Bioengineering, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Denver, Colo (A.J.B.).
  • Joshua D Robinson
    Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
  • Cynthia K Rigsby
    Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
  • Michael Markl
    Department of Biomedical Engineering and Physics (J.T.P.) and Department of Radiology & Nuclear Medicine (P.v.O.), Academic Medical Center, Amsterdam University Medical Centers, Location AMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Department of Radiology (B.D.A., J.C.C., M.M.), Department of Medicine-Cardiology (R.O.B., L.C.), and Department of Biomedical Engineering (M.M.), Northwestern University, Chicago, Ill; and Department of Radiology & Bioengineering, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Denver, Colo (A.J.B.).