AIMC Topic: Aorta

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AI-powered automated model construction for patient-specific CFD simulations of aortic flows.

Science advances
Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and time-consumi...

Perivascular inflammation in the progression of aortic aneurysms in Marfan syndrome.

JCI insight
Inflammation plays important roles in the pathogenesis of vascular diseases. We here show the involvement of perivascular inflammation in aortic dilatation of Marfan syndrome (MFS). In the aorta of patients with MFS and Fbn1C1041G/+ mice, macrophages...

Detection of aging-induced vascular remodeling based on Raman imaging and deep learning.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Vascular aging-related remodeling is a common pathological basis for many chronic diseases, so early detection of physical arterial aging is important for their prevention and control. Existing staining methods can only analyze a limited number of ti...

Exploring the Incremental Value of Aorta Enhancement Normalization Method in Evaluating Renal Cell Carcinoma Histological Subtypes: A Multi-center Large Cohort Study.

Academic radiology
RATIONALE AND OBJECTIVES: The classification of renal cell carcinoma (RCC) histological subtypes plays a crucial role in clinical diagnosis. However, traditional image normalization methods often struggle with discrepancies arising from differences i...

Non-invasive estimation of beat-by-beat aortic blood pressures from electrical impedance tomography data processed by machine learning.

Journal of clinical monitoring and computing
Hypotension in perioperative and intensive care settings is a significant risk factor associated with complications such as myocardial infarction and kidney injury thereby increasing perioperative complications and mortality. Continuous blood pressur...

A spectral machine learning approach to derive central aortic pressure waveforms from a brachial cuff.

Proceedings of the National Academy of Sciences of the United States of America
Analyzing cardiac pulse waveforms offers valuable insights into heart health and cardiovascular disease risk, although obtaining the more informative measurements from the central aorta remains challenging due to their invasive nature and limited non...

Association Between Aortic Imaging Features and Impaired Glucose Metabolism: A Deep Learning Population Phenotyping Approach.

Academic radiology
RATIONALE AND OBJECTIVES: Type 2 diabetes is a known risk factor for vascular disease with an impact on the aorta. The aim of this study was to develop a deep learning framework for quantification of aortic phenotypes from magnetic resonance imaging ...

Generalizability, robustness, and correction bias of segmentations of thoracic organs at risk in CT images.

European radiology
OBJECTIVE: This study aims to assess and compare two state-of-the-art deep learning approaches for segmenting four thoracic organs at riskĀ (OAR)-the esophagus, trachea, heart, and aorta-in CT images in the context of radiotherapy planning.

Development of a Self-Deploying Extra-Aortic Compression Device for Medium-Term Hemodynamic Stabilization: A Feasibility Study.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Hemodynamic stabilization is crucial in managing acute cardiac events, where compromised blood flow can lead to severe complications and increased mortality. Conditions like decompensated heart failure (HF) and cardiogenic shock require rapid and eff...

Pinning down the accuracy of physics-informed neural networks under laminar and turbulent-like aortic blood flow conditions.

Computers in biology and medicine
BACKGROUND: Physics-informed neural networks (PINNs) are increasingly being used to model cardiovascular blood flow. The accuracy of PINNs is dependent on flow complexity and could deteriorate in the presence of highly-dynamical blood flow conditions...