Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and time-consumi...
Inflammation plays important roles in the pathogenesis of vascular diseases. We here show the involvement of perivascular inflammation in aortic dilatation of Marfan syndrome (MFS). In the aorta of patients with MFS and Fbn1C1041G/+ mice, macrophages...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Aug 15, 2025
Vascular aging-related remodeling is a common pathological basis for many chronic diseases, so early detection of physical arterial aging is important for their prevention and control. Existing staining methods can only analyze a limited number of ti...
RATIONALE AND OBJECTIVES: The classification of renal cell carcinoma (RCC) histological subtypes plays a crucial role in clinical diagnosis. However, traditional image normalization methods often struggle with discrepancies arising from differences i...
Journal of clinical monitoring and computing
Mar 25, 2025
Hypotension in perioperative and intensive care settings is a significant risk factor associated with complications such as myocardial infarction and kidney injury thereby increasing perioperative complications and mortality. Continuous blood pressur...
Proceedings of the National Academy of Sciences of the United States of America
Feb 26, 2025
Analyzing cardiac pulse waveforms offers valuable insights into heart health and cardiovascular disease risk, although obtaining the more informative measurements from the central aorta remains challenging due to their invasive nature and limited non...
RATIONALE AND OBJECTIVES: Type 2 diabetes is a known risk factor for vascular disease with an impact on the aorta. The aim of this study was to develop a deep learning framework for quantification of aortic phenotypes from magnetic resonance imaging ...
OBJECTIVE: This study aims to assess and compare two state-of-the-art deep learning approaches for segmenting four thoracic organs at riskĀ (OAR)-the esophagus, trachea, heart, and aorta-in CT images in the context of radiotherapy planning.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Dec 27, 2024
Hemodynamic stabilization is crucial in managing acute cardiac events, where compromised blood flow can lead to severe complications and increased mortality. Conditions like decompensated heart failure (HF) and cardiogenic shock require rapid and eff...
BACKGROUND: Physics-informed neural networks (PINNs) are increasingly being used to model cardiovascular blood flow. The accuracy of PINNs is dependent on flow complexity and could deteriorate in the presence of highly-dynamical blood flow conditions...
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