Applying Machine Learning in Liver Disease and Transplantation: A Comprehensive Review.

Journal: Hepatology (Baltimore, Md.)
Published Date:

Abstract

Machine learning (ML) utilizes artificial intelligence to generate predictive models efficiently and more effectively than conventional methods through detection of hidden patterns within large data sets. With this in mind, there are several areas within hepatology where these methods can be applied. In this review, we examine the literature pertaining to machine learning in hepatology and liver transplant medicine. We provide an overview of the strengths and limitations of ML tools and their potential applications to both clinical and molecular data in hepatology. ML has been applied to various types of data in liver disease research, including clinical, demographic, molecular, radiological, and pathological data. We anticipate that use of ML tools to generate predictive algorithms will change the face of clinical practice in hepatology and transplantation. This review will provide readers with the opportunity to learn about the ML tools available and potential applications to questions of interest in hepatology.

Authors

  • Ashley Spann
    Vanderbilt University Medical Center, , Nashville, USA.
  • Angeline Yasodhara
    Vector Institute for Artificial Intelligence, Toronto, ON, Canada.
  • Justin Kang
    Multi Organ Transplant Program, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada.
  • Kymberly Watt
    Division of Gastroenterology, Mayo Clinic, Rochester, MN.
  • Bo Wang
    Department of Clinical Laboratory Medicine Center, Inner Mongolia Autonomous Region People's Hospital, Hohhot, Inner Mongolia, China.
  • Anna Goldenberg
    SickKids Research Institute, 686 Bay Street, Toronto, ON M5G 0A4, Canada; Department of Computer Science, University of Toronto, 40 St. George Street, Toronto, ON M5S 2E4, Canada. Electronic address: anna.goldenberg@utoronto.ca.
  • Mamatha Bhat
    Transplant AI Initiative, Ajmera Transplant Program, University Health Network, Toronto, ON, Canada.