BACKGROUND: Hepatic ischemia-reperfusion injury (HIRI) represents the leading cause of postoperative liver dysfunction and failure. Ammonia-induced cell death (ACD), defined by lysosomal and mitochondrial disruption due to intracellular ammonia accum...
Clinica chimica acta; international journal of clinical chemistry
Sep 1, 2025
Bilirubin is a vital biomarker that plays a significant role in assessing liver function and diagnosing hemolytic disorders. While current detection methods are indeed sufficient for clinical practice, the accurate and timely detection of bilirubin l...
Understanding diseases as the result of continuous transitions from a healthy system is more realistic than understanding them as discrete states. Here, we designed the spectrum formation approach (SFA), a machine learning-based method that extracts ...
Liver disease encompasses a range of conditions affecting the liver, including hepatitis, cirrhosis, fatty liver, and liver cancer. It can be caused by infections, alcohol abuse, obesity, or genetic factors, and it often progresses silently until adv...
BACKGROUND: We aimed to quantify hepatic vessel volumes across chronic liver disease stages and healthy controls using deep learning-based magnetic resonance imaging (MRI) analysis, and assess correlations with biomarkers for liver (dys)function and ...
BACKGROUND: Prognostication in chronic liver disease and the implementation of appropriate scoring systems is difficult given the variety of clinical manifestations. It is important to understand the limitations of each scoring system as well as the ...
Phytomedicine : international journal of phytotherapy and phytopharmacology
Apr 23, 2025
BACKGROUND AND PURPOSE: The progression from hepatitis to liver fibrosis (LF) and ultimately to hepatic carcinoma (HCC) represents the advanced stages of various liver diseases. Currently, no universal treatment effectively addresses all three condit...
Reports indicate a growing role for artificial intelligence (AI) in the evaluation of pancreaticobiliary and hepatic conditions. A key focus is differentiating between benign and malignant lesions, which is crucial for treatment decisions. AI improve...
Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
Feb 27, 2025
Large language models (LLMs) have the potential to support clinical decision-making but often lack training on the latest clinical guidelines. Retrieval-augmented generation (RAG) may enhance guideline adherence by dynamically integrating external i...
International journal of medical informatics
Feb 17, 2025
BACKGROUND: Liver disease accounts for 4 % of global mortality. The advent of mobile technology has introduced a novel domain in liver disease management. Identifying effective mobile apps with pertinent information on liver diseases is essential. Th...
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