Comparison of statistical and machine learning models for healthcare cost data: a simulation study motivated by Oncology Care Model (OCM) data.

Journal: BMC health services research
PMID:

Abstract

BACKGROUND: The Oncology Care Model (OCM) was developed as a payment model to encourage participating practices to provide better-quality care for cancer patients at a lower cost. The risk-adjustment model used in OCM is a Gamma generalized linear model (Gamma GLM) with log-link. The predicted value of expense for the episodes identified for our academic medical center (AMC), based on the model fitted to the national data, did not correlate well with our observed expense. This motivated us to fit the Gamma GLM to our AMC data and compare it with two other flexible modeling methods: Random Forest (RF) and Partially Linear Additive Quantile Regression (PLAQR). We also performed a simulation study to assess comparative performance of these methods and examined the impact of non-linearity and interaction effects, two understudied aspects in the field of cost prediction.

Authors

  • Madhu Mazumdar
    Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Jung-Yi Joyce Lin
    Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Wei Zhang
    The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Lihua Li
    College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University, Hangzhou 310018, China. Electronic address: lilh@hdu.edu.cn.
  • Mark Liu
    Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, 10029, USA.
  • Kavita Dharmarajan
    Department of Radiation Oncology, Brookdale Department of Geriatrics and Palliative Medicine Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York, USA.
  • Mark Sanderson
    Department of Health System Design and Global Health, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Luis Isola
    Tisch Cancer Institute, Mount Sinai Hospital, New York, NY, 10029, USA.
  • Liangyuan Hu
    Institute for Healthcare Delivery Science, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. liangyuan.hu@mountsinai.org.